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Article

TRPV6 variants confer susceptibility to chronic pancreatitis in the Chinese population.

Human mutation - 1 Aug 2020

Zou Wen-Bin, Wang Yuan-Chen, Ren Xin-Lu, Wang Lei, Deng Shun-Jiang, Mao Xiao-Tong, Li Zhao-Shen, Liao Zhuan

Abstract excerpt

Chronic pancreatitis (CP) is a progressive fibroinflammatory syndrome of the pancreatic tissue caused by genetic and environmental factors. Previously reported susceptibility genes in CP explain less than half of the apparent heritability. To uncover novel pathogenic mechanisms, we initially performed low-coverage whole-genome sequencing on 464 Chinese CP patients and 504 controls. The transient receptor...

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PMID: 32383311
DOI: 10.1002/humu.24032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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