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Article

TRPV6, a new entrant as a susceptibility gene in chronic pancreatitis: evidence from a systematic review and meta-analysis.

BMC gastroenterology - 10 Jan 2026

Shah Idrees A, Ganie Jabish, Bhat Gulzar A, Rashid Aamir, Wani Rauf A

Abstract excerpt

BACKGROUND: Pancreatitis, a debilitating disease, is orchestrated by many etiological factors. Besides the known causal genes, including PRSS1, SPINK1, CPA1, CFTR, etc., of late, TRPV6 has emerged as a new candidate in the list. We aimed to investigate the role of TRPV6 and its genetic variations in the etiopathology of pancreatitis. METHODS: We conducted a systematic review and meta-analysis of published...

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Source

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Identifiers

PMID: 41514216
DOI: 10.1186/s12876-025-04593-5
PMCID: PMC12882601

Genes

TRPV6
CFTR
CPA1
PRSS1
SPINK1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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