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Article

The Coexistence of TRPV6 Variants With Other Pancreatitis-Associated Genes Affects Pediatric-Onset Pancreatitis.

Journal of pediatric gastroenterology and nutrition - 1 Apr 2023

Hirai Saeko, Suzuki Mitsuyoshi, Sakurai Yumiko, Nakano Satoshi, Minowa Kei, Eguchi Hidetake, Okazaki Yasushi, Shimizu Toshiaki

Abstract excerpt

OBJECTIVES: Recently, a genetic risk for chronic pancreatitis (CP) was found to be conferred by pathogenic variants in the transient receptor potential cation channel, subfamily V, member 6 ( TRPV6 ). Interestingly, 20%-57% of patients with functionally defective TRPV6 variants have other susceptibility genes such as cationic trypsinogen, serine protease inhibitor Kazal type 1, chymotrypsin C, cystic fibrosis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36599151
DOI: 10.1097/MPG.0000000000003700

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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