Article
The positions of TFIIF and TFIIE in the RNA polymerase II transcription preinitiation complex.
Nature structural & molecular biology - 1 Aug 2007
Chen Hung-Ta, Warfield Linda, Hahn Steven
Abstract excerpt
We incorporated the non-natural photoreactive amino acid p-benzoyl-L-phenylalanine (Bpa) into the RNA polymerase II (Pol II) surface surrounding the central cleft formed by the Rpb1 and Rpb2 subunits. Photo-cross-linking of preinitiation complexes (PICs) with these Pol II derivatives and hydroxyl...
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