Article
Retinal metabolic state of the proline-23-histidine rat model of retinitis pigmentosa.
American journal of physiology. Cell physiology - 1 Mar 2010
Acosta Monica L, Shin Yea-Seul, Ready Sarah, Fletcher Erica L, Christie David L, Kalloniatis Michael
Abstract excerpt
We determined the metabolic changes that precede cell death in the dystrophic proline-23-histidine (P23H) line 3 (P23H-3) rat retina compared with the normal Sprague-Dawley (SD) rat retina. Metabolite levels and metabolic enzymes were analyzed early in development and during the early stages of d...
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