Article

Metabolic features of mouse and human retinas: rods vs. cones, macula vs. periphery, retina vs. RPE

2020-07-10

Abstract excerpt

Photoreceptors, especially cones, which are enriched in the human macula, have high energy demands, making them vulnerable to metabolic stress. Metabolic dysfunction of photoreceptors and their supporting retinal pigment epithelium (RPE) is an important underlying cause of degenerative retinal diseases. However, how cones and the macula support their exorbitant metabolic demand and communicate with RPE is unclear....

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Literature Corpus work: 60c806b5-457a-5ce7-9dab-f7527b3f3372
DOI: 10.1101/2020.07.10.196295

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