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Article

Mapping cation entry in photoreceptors and inner retinal neurons during early degeneration in the P23H-3 rat retina.

Visual neuroscience - 1 May 2013

Zhu Yuan, Misra Stuti, Mistra Stuti, Nivison-Smith Lisa, Acosta Monica L, Fletcher Erica L, Kalloniatis Michael

Abstract excerpt

The proline-23-histidine line 3 (P23H-3) transgenic rat carries a human opsin gene mutation leading to progressive photoreceptor loss characteristic of human autosomal dominant retinitis pigmentosa. The aim of the present study was to evaluate neurochemical modifications in the P23H-3 retina as a function of development and degeneration. Specifically, we investigated the ion channel permeability of photoreceptors...

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Identifiers

PMID: 23557623
DOI: 10.1017/S0952523813000047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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