Article

Role of Alanine Transaminase in Retinal Metabolic Homeostasis: Potential therapeutic target in retinal diseases

2026-04-22

Abstract excerpt

<h4>Purpose</h4> Alanine transaminases (ALT), encoded by the GPT gene, catalyzes the reversible conversion of pyruvate and glutamate to alanine and alpha-ketoglutarate, thereby correlating carbohydrate and amino acid metabolism. However, its role in the human neural retina remains unclear. This study aimed to explore the expression, localization, and metabolic function of ALT in the human neural retina and its po...

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Literature Corpus work: faba25b0-e96a-552c-981e-02b19847930d
DOI: 10.64898/2026.04.19.719493

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