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Article

Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats.

PloS one - 1 Jan 2011

Kaur Jasvir, Mencl Stine, Sahaboglu Ayse, Farinelli Pietro, van Veen Theo, Zrenner Eberhart, Ekström Per, Paquet-Durand François, Arango-Gonzalez Blanca

Abstract excerpt

Retinitis pigmentosa (RP) is a heterogeneous group of inherited neurodegenerative diseases affecting photoreceptors and causing blindness. Many human cases are caused by mutations in the rhodopsin gene. An important question regarding RP pathology is whether different genetic defects trigger the same or different cell death mechanisms. To answer this question, we analysed photoreceptor degeneration in P23H and...

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Identifiers

PMID: 21765948
DOI: 10.1371/journal.pone.0022181
PMCID: PMC3134478

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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