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Article

Müller cell metabolic chaos during retinal degeneration.

Experimental eye research - 1 Sept 2016

Pfeiffer Rebecca L, Marc Robert E, Kondo Mineo, Terasaki Hiroko, Jones Bryan W

Abstract excerpt

Müller cells play a critical role in retinal metabolism and are among the first cells to demonstrate metabolic changes in retinal stress or disease. The timing, extent, regulation, and impacts of these changes are not yet known. We evaluated metabolic phenotypes of Müller cells in the degenerating retina. Retinas harvested from wild-type (WT) and rhodopsin Tg P347L rabbits were fixed in mixed aldehydes and resin...

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Identifiers

PMID: 27142256
DOI: 10.1016/j.exer.2016.04.022
PMCID: PMC5031519

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