Article
Association of the GNAS1 T393C polymorphism with tumor stage and survival in gastric cancer.
World journal of gastroenterology - 28 Dec 2009
Alakus Hakan, Mönig Stefan P, Warnecke-Eberz Ute, Alakus Gül, Winde Günther, Drebber Uta, Schmitz Klaus J, Schmid Kurt W, Riemann Kathrin, Siffert Winfried, Bollschweiler Elfriede, Hölscher Arnulf H, Metzger Ralf
Abstract excerpt
AIM: To analyze the impact of the GNAS1 T393C polymorphism on prognosis and histopathology of gastric cancer. METHODS: Genomic DNA was extracted from paraffin-embedded tissues of 122 patients with primary gastric carcinoma and from the blood of 820 healthy white individuals. Allelic discrimination was performed by quantitative real-time polymerase chain reaction. Genotyping was correlated with histopathologic...
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