Article
The T393C polymorphism of GNAS1 is a predictor for relapse and survival in resectable non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Feb 2013
Uzunoglu Faik Güntac, Heumann Asmus, Musici Safije, Kutup Asad, Koenig Alexandra, Roch Nadine, Thomssen Adriana, Dohrmann Thorsten, Tsui Tung Yu, Mann Oliver, Izbicki Jakob Robert, Vashist Yogesh Kumar
Abstract excerpt
INTRODUCTION: The GNAS1 T393C single nucleotide polymorphism (T393C-SNP) correlates with Gαs mRNA stability and protein expression and augmented apoptosis. Genetic germ line variations as stable and reproducible markers potentially serve as prognostic marker in oncology. The aim of this study was...
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