Article
DNA methyltransferase 3a rs1550117 genetic polymorphism predicts poor survival in gastric cancer patients.
International journal of clinical and experimental pathology - 1 Jan 2015
Wang Chuan, Jia Zhifang, Ma Hongxi, Cao Donghui, Wu Xing, Wen Simin, You Lili, Cao Xueyuan, Jiang Jing
Abstract excerpt
DNA methyltransferase 3a (DNMT3a) have been suggested to play a crucial role in human cancer prognosis. Single nucleotide polymorphisms (SNPs) in DNMT3a genes may have an impact on the prognosis of cancers. This study aimed to investigate the association between SNPs of DNMT3a gene and prognosis of gastric cancer (GC). Two sites of DNMT3a SNPs, rs1550117 and rs13420827 were selected and genotyped using TaqMan...
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