Article
Heterozygosity for CCR5-Delta32 but not CCR2b-64I protects against certain intracellular pathogens.
HIV medicine - 1 Apr 2002
Ashton L J, Stewart G J, Biti R, Law M, Cooper D A, Kaldor J M
Abstract excerpt
OBJECTIVE: To determine the association between CCR5 and CCR2b genotype and the clinical manifestation of first and subsequent AIDS-defining illnesses (ADIs). METHODS: The distribution of ADIs was examined by CCR5 and CCR2b genotype in a subset of homosexual men enrolled in the Sydney AIDS Prospective Study. The expected number of ADIs was calculated from rates observed in the same tertiary hospital over the same...
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