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Article

Primary acute dengue and the deletion in chemokine receptor 5 (CCR5Δ32).

Microbes and infection - 1 Jun 2014

Brestovac Brian, Halicki Larissa A, Harris Ryan P, Sampson Ian, Speers David J, Mamotte Cyril, Williams David

Abstract excerpt

Dengue virus is a significant arboviral pathogen that is continuing to spread due to human travel and invasion of the mosquito vectors into new regions. Chemokine receptor 5 (CCR5) has a truncated 32 base pair deletion form (CCR5Δ32), which has been associated with resistance to HIV but increased severity in some flaviviral diseases. If CCR5Δ32 is associated with dengue, European carriers of this mutation may be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24607451
DOI: 10.1016/j.micinf.2014.02.007

Genes

CCR5

Provenance

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