Article
Deep short-read sequencing of chromosome 17 from the mouse strains A/J and CAST/Ei identifies significant germline variation and candidate genes that regulate liver triglyceride levels.
Genome biology - 1 Jan 2009
Sudbery Ian, Stalker Jim, Simpson Jared T, Keane Thomas, Rust Alistair G, Hurles Matthew E, Walter Klaudia, Lynch Dee, Teboul Lydia, Brown Steve D, Li Heng, Ning Zemin, Nadeau Joseph H, Croniger Colleen M, Durbin Richard, Adams David J
Abstract excerpt
Genome sequences are essential tools for comparative and mutational analyses. Here we present the short read sequence of mouse chromosome 17 from the Mus musculus domesticus derived strain A/J, and the Mus musculus castaneus derived strain CAST/Ei. We describe approaches for the accurate identification of nucleotide and structural variation in the genomes of vertebrate experimental organisms, and show how these...
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