Article
A sequence-based variation map of 8.27 million SNPs in inbred mouse strains.
Nature - 30 Aug 2007
Frazer Kelly A, Eskin Eleazar, Kang Hyun Min, Bogue Molly A, Hinds David A, Beilharz Erica J, Gupta Robert V, Montgomery Julie, Morenzoni Matt M, Nilsen Geoffrey B, Pethiyagoda Charit L, Stuve Laura L, Johnson Frank M, Daly Mark J, Wade Claire M, Cox David R
Abstract excerpt
A dense map of genetic variation in the laboratory mouse genome will provide insights into the evolutionary history of the species and lead to an improved understanding of the relationship between inter-strain genotypic and phenotypic differences. Here we resequence the genomes of four wild-derived and eleven classical strains. We identify 8.27 million high-quality single nucleotide polymorphisms (SNPs) densely...
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