Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A new permutation strategy of pathway-based approach for genome-wide association study.

BMC bioinformatics - 18 Dec 2009

Guo Yan-Fang, Li Jian, Chen Yuan, Zhang Li-Shu, Deng Hong-Wen

Abstract excerpt

BACKGROUND: Recently introduced pathway-based approach is promising and advantageous to improve the efficiency of analyzing genome-wide association scan (GWAS) data to identify disease variants by jointly considering variants of the genes that belong to the same biological pathway. However, the current available pathway-based approaches for analyzing GWAS have limited power and efficiency. RESULTS: We proposed a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Computational Biology
Share to Databases, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genetic Variation

Share to Genome-Wide Association Study

Share to Genotype

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 20021635
DOI: 10.1186/1471-2105-10-429
PMCID: PMC2809078

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A new permutation strategy of pathway-based approach for genome-wide association study.PMID 20021635Read ↗

Systematic permutation testing in GWAS pathway analyses: identification of genetic networks in dilated cardiomyopathy and ulcerative colitis.Semantic proximity Read ↗

GWAS summary-based pathway analysis correcting for the genetic confounding impact of environmental exposures.Semantic proximity Read ↗

Improving the detection of pathways in genome-wide association studies by combined effects of SNPs from Linkage Disequilibrium blocks.Semantic proximity Read ↗

Gene and pathway-based second-wave analysis of genome-wide association studies.Semantic proximity Read ↗

Efficient pathway enrichment and network analysis of GWAS summary data using GSA-SNP2.Semantic proximity Read ↗

Uncovering networks from genome-wide association studies via circular genomic permutation.Semantic proximity Read ↗

Analysing biological pathways in genome-wide association studies.Semantic proximity Read ↗

Pathway-based approaches for analysis of genomewide association studies.Semantic proximity Read ↗

Pathway-PDT: a flexible pathway analysis tool for nuclear families.Semantic proximity Read ↗

A two-stage random forest-based pathway analysis method.Semantic proximity Read ↗

Identification of SNP Targeted Pathways From Genome-wide Association Study (GWAS) DataSemantic proximity Read ↗

Pathway-based analysis using reduced gene subsets in genome-wide association studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.