Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pathway-based analysis using reduced gene subsets in genome-wide association studies.

BMC bioinformatics - 12 Jan 2011

Zhao Jingyuan, Gupta Simone, Seielstad Mark, Liu Jianjun, Thalamuthu Anbupalam

Abstract excerpt

BACKGROUND: Single Nucleotide Polymorphism (SNP) analysis only captures a small proportion of associated genetic variants in Genome-Wide Association Studies (GWAS) partly due to small marginal effects. Pathway level analysis incorporating prior biological information offers another way to analyze GWAS's of complex diseases, and promises to reveal the mechanisms leading to complex diseases. Biologically defined...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes
Share to Genetic Variation
Share to Genome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Psoriasis

Source

Open in PubMed Open full text

Identifiers

PMID: 21226955
DOI: 10.1186/1471-2105-12-17
PMCID: PMC3033801

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pathway-based analysis using reduced gene subsets in genome-wide association studies.PMID 21226955Read ↗

Identifying disease related sub-pathways for analysis of genome-wide association studies.Semantic proximity Read ↗

Strategies for pathway analysis from GWAS data.Semantic proximity Read ↗

Pathway-based approaches for analysis of genomewide association studies.Semantic proximity Read ↗

Analysing biological pathways in genome-wide association studies.Semantic proximity Read ↗

Gene and pathway-based second-wave analysis of genome-wide association studies.Semantic proximity Read ↗

Genome-wide gene and pathway analysis.Semantic proximity Read ↗

Functional and genomic context in pathway analysis of GWAS data.Semantic proximity Read ↗

Using genome-wide pathway analysis to unravel the etiology of complex diseases.Semantic proximity Read ↗

Genome-Wide Pathway Analysis Identifies Genetic Pathways Associated with Psoriasis.Semantic proximity Read ↗

Pathway Analysis Incorporating Protein-Protein Interaction Networks Identified Candidate Pathways for the Seven Common Diseases.Semantic proximity Read ↗

Pathway analysis of complex diseases for GWAS, extending to consider rare variants, multi-omics and interactions.Semantic proximity Read ↗

Improving the detection of pathways in genome-wide association studies by combined effects of SNPs from Linkage Disequilibrium blocks.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.