Article
Pathway-PDT: a flexible pathway analysis tool for nuclear families.
BMC bioinformatics - 4 Sept 2013
Park Yo Son, Schmidt Michael, Martin Eden R, Pericak-Vance Margaret A, Chung Ren-Hua
Abstract excerpt
BACKGROUND: Pathway analysis based on Genome-Wide Association Studies (GWAS) data has become popular as a secondary analysis strategy. Although many pathway analysis tools have been developed for case-control studies, there is no tool that can use all information from raw genotypes in general nuclear families. We developed Pathway-PDT, which uses the framework of Pedigree Disequilibrium Test (PDT) for general...
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