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Article

HLA-DQA1 and HLA-DQB1 genes may jointly determine susceptibility to develop multiple sclerosis.

Human immunology - 1 Jan 1991

Spurkland A, Rønningen K S, Vandvik B, Thorsby E, Vartdal F

Abstract excerpt

Serologic DR typing and genomic DRB1, DQA1, DQB1, DPA1, and DPB1 typing using sequence-specific oligonucleotides were performed in 69 multiple sclerosis (MS) patients and 181 healthy controls on in vitro amplified DNA. The frequencies of DR2 as well as the DR2-associated DQA1*0102 and DQB1*0602 alleles were increased whereas DR7 was decreased among MS patients. The distribution of DR4 subtypes as well as DP...

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Source

Identifiers

PMID: 2001977
DOI: 10.1016/0198-8859(91)90073-i

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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