Article
Analysis of HLA-class II DQA1, DQB1, DRB1 and DPB1 in Italian multiple sclerosis patients.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Apr 1995
Ciusani E, Allen M, Sandberg-Wollheim M, Eoli M, Salmaggi A, Milanese C, Nespolo A, Gyllensten U
Abstract excerpt
We studied the allelic constitution at the HLA class II DQA1, DQB1, DRB1 and DPB1 in 94 Italian multiple sclerosis (MS) patients and 98 controls. No significant increase in the frequency of DR2 alleles was detected among MS patients, as previously observed both in European and some Italian studie...
Topics
- Alleles
- Disease Susceptibility
- Gene Frequency
- Genes, MHC Class II
- Genetic Predisposition to Disease
- HLA-D Antigens
- HLA-DP Antigens
- HLA-DP beta-Chains
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- HLA-DR Antigens
- HLA-DRB1 Chains
- Humans
- Italy
- Multiple Sclerosis