Article
HLA-DRB1, -DQA1, -DQB1, -DPA1 and -DPB1 genes in Japanese multiple sclerosis patients.
Tissue antigens - 1 Apr 1991
Spurkland A, Tabira T, Rønningen K S, Vandvik B, Thorsby E, Vartdal F
Abstract excerpt
Japanese MS patients and controls were examined for the distribution of HLA-DRB1, -DQA1, -DQB1, -DPA1 and -DPB1 alleles using in vitro amplification of genomic DNA and probing with sequence-specific oligonucleotides. No significant difference in frequency of the examined alleles was observed among the two groups. This is in contrast to Norwegian MS patients, where an association to a combination of certain DQA1...
Topics
- Alleles
- Asian People
- Disease Susceptibility
- Genes, MHC Class II
- Genetic Predisposition to Disease
- HLA-D Antigens
- HLA-DP Antigens
- HLA-DP alpha-Chains
- HLA-DP beta-Chains
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
