How many probes are needed for HLA-DPB1 typing with sequence-specific oligonucleotide probes? A theoretical approach using computer simulation.

doi:10.1016/0198-8859(91)90066-i

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Article

How many probes are needed for HLA-DPB1 typing with sequence-specific oligonucleotide probes? A theoretical approach using computer simulation.

Human immunology - 1 Jan 1991

Müller C R, Eiermann T H

Abstract excerpt

HLA-DP genotyping with sequence-specific oligonucleotides is used to detect known sequence variations in the polymorphic segments of the DPB1 second exon. This approach is a valuable method replacing the tedious cellular definition of DP polymorphism. We have addressed, by computer simulation, th...

Topics

Alleles
Computer Simulation
Genotype
HLA-DP Antigens
Histocompatibility Testing
Humans
Molecular Probes
Oligonucleotides

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