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Article

Techniques used to define human MHC antigens: polymerase chain reaction and oligonucleotide probes.

Immunology letters - 1 Jul 1991

Wordsworth P

Abstract excerpt

The various HLA class II specificities, identifiable by serological or cellular typing reagents, reflect underlying polymorphisms of the constituent alpha and beta chains, encoded at several loci within the HLA-D region. Variation in these genes is concentrated in allelic hypervariable regions but can also be found elsewhere. Sequence-specific oligonucleotides (SSO) can be used to detect individual alleles with a...

Topics

Alleles
HLA-D Antigens
Histocompatibility Testing
Humans
Oligonucleotide Probes
Polymerase Chain Reaction
Polymorphism, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1916922
DOI: 10.1016/0165-2478(91)90196-h

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1916922-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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