Article
Genomewide association study of leprosy.
The New England journal of medicine - 31 Dec 2009
Zhang Fu-Ren, Huang Wei, Chen Shu-Min, Sun Liang-Dan, Liu Hong, Li Yi, Cui Yong, Yan Xiao-Xiao, Yang Hai-Tao, Yang Rong-De, Chu Tong-Sheng, Zhang Chi, Zhang Lin, Han Jian-Wen, Yu Gong-Qi, Quan Cheng, Yu Yong-Xiang, Zhang Zheng, Shi Ben-Qing, Zhang Lian-Hua, Cheng Hui, Wang Chang-Yuan, Lin Yan, Zheng Hou-Feng, Fu Xi-An, Zuo Xian-Bo, Wang Qiang, Long Heng, Sun Yi-Ping, Cheng Yi-Lin, Tian Hong-Qing, Zhou Fu-Sheng, Liu Hua-Xu, Lu Wen-Sheng, He Su-Min, Du Wen-Li, Shen Min, Jin Qi-Yi, Wang Ying, Low Hui-Qi, Erwin Tantoso, Yang Ning-Han, Li Jin-Yong, Zhao Xin, Jiao Yue-Lin, Mao Li-Guo, Yin Gang, Jiang Zhen-Xia, Wang Xiao-Dong, Yu Jing-Ping, Hu Zong-Hou, Gong Cui-Hua, Liu Yu-Qiang, Liu Rui-Yu, Wang De-Min, Wei Dong, Liu Jin-Xian, Cao Wei-Kun, Cao Hong-Zhong, Li Yong-Ping, Yan Wei-Guo, Wei Shi-Yu, Wang Kui-Jun, Hibberd Martin L, Yang Sen, Zhang Xue-Jun, Liu Jian-Jun
Abstract excerpt
BACKGROUND: The narrow host range of Mycobacterium leprae and the fact that it is refractory to growth in culture has limited research on and the biologic understanding of leprosy. Host genetic factors are thought to influence susceptibility to infection as well as disease progression. METHODS: We performed a two-stage genomewide association study by genotyping 706 patients and 1225 controls using the...
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