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Article

Association of the rs2111234, rs3135499, rs8057341 polymorphisms in the NOD2 gene with leprosy: A case-control study in the Norte de Santander, Colombia population.

PloS one - 1 Jan 2023

Bustos Mónica Alexandra, Castañeda-Castañeda Luz Dary, Acosta Carmen Rosa, García Diana, Bohada Diana Patricia, Rodríguez Raúl, Guerrero Martha Inírida

Abstract excerpt

BACKGROUND: Leprosy is a chronic infectious disease caused by Mycobacterium leprae. The development of leprosy involves several factors, including the causative agent, the individual host's immune response, environmental factors, and the genetic background of the host. Specifically, the host's innate immune response, encoded by genes, determines their susceptibility to developing leprosy post-infection....

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PMID: 36877680
DOI: 10.1371/journal.pone.0281553
PMCID: PMC9987820

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