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Article

Generation of a Magoh conditional allele in mice.

Genesis (New York, N.Y. : 2000) - 1 Aug 2014

McMahon John J, Shi Lei, Silver Debra L

Abstract excerpt

Magoh encodes a core component of the exon junction complex (EJC), which binds mRNA and regulates mRNA metabolism. Magoh is highly expressed in proliferative tissues during development. EJC components have been implicated in several developmental disorders including TAR syndrome, Richieri-Costa-Pereira syndrome, and intellectual disability. Existing germline null Magoh mice are embryonic lethal as homozygotes and...

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Identifiers

PMID: 24771530
DOI: 10.1002/dvg.22788
PMCID: PMC4111959

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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