Article
Genetic variation at the FTO locus influences RBL2 gene expression.
Diabetes - 1 Mar 2010
Jowett Jeremy B M, Curran Joanne E, Johnson Matthew P, Carless Melanie A, Göring Harald H H, Dyer Thomas D, Cole Shelley A, Comuzzie Anthony G, MacCluer Jean W, Moses Eric K, Blangero John
Abstract excerpt
OBJECTIVE: Genome-wide association studies that compare the statistical association between thousands of DNA variations and a human trait have detected 958 loci across 127 different diseases and traits. However, these statistical associations only provide evidence for genomic regions likely to harbor a causal gene(s) and do not directly identify such genes. We combined gene variation and expression data in a...
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