Article
Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue.
Diabetes - 1 Oct 2009
Grunnet Louise G, Nilsson Emma, Ling Charlotte, Hansen Torben, Pedersen Oluf, Groop Leif, Vaag Allan, Poulsen Pernille
Abstract excerpt
OBJECTIVE: Common variants in FTO (the fat mass- and obesity-associated gene) associate with obesity and type 2 diabetes. The regulation and biological function of FTO mRNA expression in target tissue is unknown. We investigated the genetic and nongenetic regulation of FTO mRNA in skeletal muscle...
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