Article
Fine mapping of the association with obesity at the FTO locus in African-derived populations.
Human molecular genetics - 15 Jul 2010
Hassanein Mohamed T, Lyon Helen N, Nguyen Thutrang T, Akylbekova Ermeg L, Waters Kevin, Lettre Guillaume, Tayo Bamidele, Forrester Terrence, Sarpong Daniel F, Stram Dan O, Butler Johannah L, Wilks Rainford, Liu Jiankang, Le Marchand Loic, Kolonel Laurence N, Zhu Xiaofeng, Henderson Brian, Cooper Richard, McKenzie Colin, Taylor Herman A, Haiman Christopher A, Hirschhorn Joel N
Abstract excerpt
Genome-wide association studies have identified many common genetic variants that are associated with polygenic traits, and have typically been performed with individuals of recent European ancestry. In these populations, many common variants are tightly correlated, with the perfect or near-perfe...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.