Article
Single nucleotide polymorphisms of the FTO gene and cancer risk: an overview.
Molecular biology reports - 1 Mar 2015
Hernández-Caballero Marta Elena, Sierra-Ramírez José Alfredo
Abstract excerpt
The FTO (fat mass and obesity-associated) gene has a strong linkage disequilibrium block, within which SNPs have been identified that are involved in the development of obesity. Recently some of these variants have also been associated with cancer. However, identification of the possible mechanisms that could explain these associations has proven to be elusive. It has been found that FTO polymorphisms can...
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