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Article

The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels.

European journal of human genetics : EJHG - 1 Sept 2010

Berulava Tea, Horsthemke Bernhard

Abstract excerpt

As shown by genome-wide association studies single-nucleotide polymorphisms (SNPs) within intron 1 of the FTO gene are associated with the body mass index and type II diabetes, although the functional significance of these SNPs has remained unclear. Using primer extension assays, we have determined the ratio of allelic FTO transcript levels in unspliced heterogeneous nuclear RNA preparations from blood of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20512162
DOI: 10.1038/ejhg.2010.71
PMCID: PMC2987405

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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