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Article

Prdm16 is required for normal palatogenesis in mice.

Human molecular genetics - 1 Mar 2010

Bjork Bryan C, Turbe-Doan Annick, Prysak Mary, Herron Bruce J, Beier David R

Abstract excerpt

Transcriptional cofactors are essential to the regulation of transforming growth factor beta (TGFbeta) superfamily signaling and play critical and widespread roles during embryonic development, including craniofacial development. We describe the cleft secondary palate 1 (csp1) N-ethyl-N-nitrosourea-induced mouse model of non-syndromic cleft palate (NSCP) that is caused by an intronic Prdm16 splicing mutation....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20007998
DOI: 10.1093/hmg/ddp543
PMCID: PMC2816611

Genes

CP
PRDM16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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