Article
Genetic Variants in METTL16 Affect the Risk of Non-Syndromic Orofacial Clefts.
Birth defects research - 1 Oct 2024
Xu Xinze, Li Xiaofeng, Han Minxuan, Xing Changyue, Zhu Guirong, Cui Xing, Wang Lin, Lou Shu, Pan Yongchu
Abstract excerpt
OBJECTIVE: N6-methyladenosine (m6A) is the most prevalent modification of RNA in eukaryotes which is associated with many cellular processes and diseases. Here, our objective is to explore whether genetic variants in m6A modification genes are associated with the risk of non-syndrome orofacial clefts (NSOCs). METHODS: The transmission disequilibrium test (TDT) was performed to calculate the association between...
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