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Article

PB2 and PA genes control the expression of the temperature-sensitive phenotype of cold-adapted B/USSR/60/69 influenza master donor virus.

The Journal of general virology - 1 Apr 2010

Kiseleva Irina V, Voeten J Theo M, Teley Lisette C P, Larionova Natalia V, Drieszen-van der Cruijsen Sandra K M, Basten Stephanie M C, Heldens Jacco G M, van den Bosch Han, Rudenko Larisa G

Abstract excerpt

The cold-adapted (ca) and temperature-sensitive (ts) influenza master donor virus (MDV) B/USSR/60/69 was derived from its wild-type parental virus after successive passages in eggs at 32 degrees C and 25 degrees C. This strain is currently in use for preparing reassortant influenza B vaccine viruses which are used in the Russian trivalent live attenuated influenza vaccine. Vaccine viruses are obtained by...

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Identifiers

PMID: 20007357
DOI: 10.1099/vir.0.017996-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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