Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular basis of live-attenuated influenza virus.

PloS one - 1 Jan 2013

He Wen, Wang Wei, Han Huamin, Wang Lei, Zhang Ge, Gao Bin

Abstract excerpt

Human influenza is a seasonal disease associated with significant morbidity and mortality. The most effective means for controlling infection and thereby reducing morbidity and mortality is vaccination with a three inactivated influenza virus strains mixture, or by intranasal administration of a group of three different live attenuated influenza vaccine strains. Comparing to the inactivated vaccine, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Viral Proteins
Share to Gene Expression Regulation, Viral
Share to Influenza A Virus, H1N1 Subtype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Influenza, Human

Share to Influenza Vaccines

Share to Orthomyxoviridae Infections

Share to RNA-Dependent RNA Polymerase

Share to Vaccines, Attenuated

Source

Open in PubMed Open full text

Identifiers

PMID: 23555969
DOI: 10.1371/journal.pone.0060413
PMCID: PMC3608614

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular basis of live-attenuated influenza virus.PMID 23555969Read ↗

Temperature Sensitive Mutations in Influenza A Viral Ribonucleoprotein Complex Responsible for the Attenuation of the Live Attenuated Influenza VaccineSemantic proximity Read ↗

Live-attenuated influenza virus vaccine strain with an engineered temperature-sensitive and genetically stable viral polymerase variant.Semantic proximity Read ↗

Comparative Study of the Temperature Sensitive, Cold Adapted and Attenuated Mutations Present in the Master Donor Viruses of the Two Commercial Human Live Attenuated Influenza Vaccines.Semantic proximity Read ↗

Genetic Basis of Attenuation of Cold-Adapted Influenza Strain B/Leningrad/14/17/55 - Backup Master Donor Virus for Influenza Type B Live Attenuated Vaccines.Semantic proximity Read ↗

Reversion of Cold-Adapted Live Attenuated Influenza Vaccine into a Pathogenic VirusSemantic proximity Read ↗

Naturally occurring PAE206K point mutation in 2009 H1N1 pandemic influenza viruses impairs viral replication at high temperatures.Semantic proximity Read ↗

A new generation of modified live-attenuated avian influenza viruses using a two-strategy combination as potential vaccine candidates.Semantic proximity Read ↗

Single PA mutation as a high yield determinant of avian influenza vaccines.Semantic proximity Read ↗

The applications of live attenuated influenza a virus with modified NS1 geneSemantic proximity Read ↗

New aspects of influenza virusesSemantic proximity Read ↗

Modifications in the Polymerase Genes of a Swine-Like Triple-Reassortant Influenza Virus To Generate Live Attenuated Vaccines against 2009 Pandemic H1N1 VirusesSemantic proximity Read ↗

Genetic bases of the temperature-sensitive phenotype of a master donor virus used in live attenuated influenza vaccines: A/Leningrad/134/17/57 (H2N2).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.