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Article

An intermolecular RNA triplex provides insight into structural determinants for the pseudoknot stimulator of -1 ribosomal frameshifting.

Nucleic acids research - 1 Mar 2010

Chou Ming-Yuan, Chang Kung-Yao

Abstract excerpt

An efficient -1 programmed ribosomal frameshifting (PRF) signal requires an RNA slippery sequence and a downstream RNA stimulator, and the hairpin-type pseudoknot is the most common stimulator. However, a pseudoknot is not sufficient to promote -1 PRF. hTPK-DU177, a pseudoknot derived from human telomerase RNA, shares structural similarities with several -1 PRF pseudoknots and is used to dissect the roles of...

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Identifiers

PMID: 20007152
DOI: 10.1093/nar/gkp1107
PMCID: PMC2836554

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Source receipt: pubmed, retrieved 7 Sept 2026.

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