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Article

A role for a novel 'trans-pseudoknot' RNA-RNA interaction in the functional dimerization of human telomerase.

Genes & development - 1 May 2003

Ly Hinh, Xu Lifeng, Rivera Melissa A, Parslow Tristram G, Blackburn Elizabeth H

Abstract excerpt

The integral RNA (hTER) of the human telomerase ribonucleoprotein has a conserved secondary structure that contains a potential pseudoknot. Here we examine the role of an intermolecular hTER-hTER interaction in the previously reported functional dimerization of telomerase. We provide evidence that the two conserved, complementary sequences of one stem of the hTER pseudoknot domain can pair intermolecularly in...

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Identifiers

PMID: 12730131
DOI: 10.1101/gad.1060803
PMCID: PMC196051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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