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Article

Functional Characterization of Human Cysteinyl Leukotriene 1 Receptor Gene Structure

1 Oct 2005

Abstract excerpt

The 5-lipoxygenase pathway has been strongly implicated in the pathogenesis of chronic inflammatory disorders, such as bronchial asthma and atherosclerosis. Cysteinyl leukotrienes (cysLTs), 5-lipoxygenase pathway products, are recognized now not only as important factors in asthmatic inflammation, but also as mediators of cell trafficking and innate immune responses. To study a role of cysLTs in inflammatory...

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PMID: 16210619
DOI: 10.4049/jimmunol.175.8.5152

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