DYRK1A genetic variants are not linked to Alzheimer's disease in a Spanish case-control cohort.

doi:10.1186/1471-2350-10-129

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Article

DYRK1A genetic variants are not linked to Alzheimer's disease in a Spanish case-control cohort.

BMC medical genetics - 8 Dec 2009

Vázquez-Higuera José Luis, Sánchez-Juan Pascual, Rodríguez-Rodríguez Eloy, Mateo Ignacio, Pozueta Ana, Frank Ana, Sastre Isabel, Valdivieso Fernando, Berciano José, Bullido María J, Combarros Onofre

Abstract excerpt

BACKGROUND: As dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) has been implicated in the abnormal hyperphosphorylation of tau in Alzheimer's disease (AD) brain, and the development of neurofibrillary tangles, we examined the contribution of this gene to the susceptibility for AD. METHODS: We examined genetic variations of DYRK1A by genotyping haplotype tagging SNPs (htSNPs) (rs11701483,...

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PMID: 19995442
DOI: 10.1186/1471-2350-10-129
PMCID: PMC2797783

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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