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Article

Caspase-1 genetic variation is not associated with Alzheimer's disease risk.

BMC medical genetics - 25 Feb 2010

Vázquez-Higuera José Luis, Rodríguez-Rodríguez Eloy, Sánchez-Juan Pascual, Mateo Ignacio, Pozueta Ana, Martínez-García Ana, Frank Ana, Valdivieso Fernando, Berciano José, Bullido María J, Combarros Onofre

Abstract excerpt

BACKGROUND: Interleukin (IL)-1beta is a potent proinflammatory cytokine markedly overexpressed in the brains of patients with Alzheimer's disease (AD), and also involved in development of atherosclerosis and coronary artery disease. Caspase-1 (CASP1), formerly called IL-1beta converting enzyme (I...

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Source

Open in PubMed Open full text

Identifiers

PMID: 20184726
DOI: 10.1186/1471-2350-11-32
PMCID: PMC2837022

Genes

CASP1
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20184726-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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