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Article

Analysis of PTPRK polymorphisms in association with risk and age at onset of Alzheimer's disease, cancer risk, and cholesterol.

Journal of psychiatric research - 1 Jan 2018

Chen Yang, Xu Chun, Harirforoosh Sam, Luo Xingguang, Wang Ke-Sheng

Abstract excerpt

The human receptor-type protein-tyrosine phosphatase kappa (PTPRK) gene is highly expressed in human brain and was previously associated with an increased risk of neuropsychiatric disorders and cancer. This study investigated the association of 52 single nucleotide polymorphisms (SNPs) in PTPRK with the risk and age at onset (AAO) of Alzheimer's disease (AD) in 791 AD patients and 782 controls. Our data analysis...

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Identifiers

PMID: 28987514
DOI: 10.1016/j.jpsychires.2017.09.021
PMCID: PMC6195678

Genes

PTPRK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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