Article
The MTHFD1L gene rs11754661 marker is not associated with Alzheimer's disease in a sample of the Spanish population.
Journal of Alzheimer's disease : JAD - 1 Jan 2011
Ramírez-Lorca Reposo, Boada Mercé, Antúnez Carmen, López-Arrieta Jesús, Moreno-Rey Concha, Hernández Isabel, Marín Juan, Gayán Javier, González-Pérez Antonio, Alegret Montserrat, Tárraga Lluis, Real Luis M, Ruiz Agustín
Abstract excerpt
The MTHFD1L gene SNP variant rs11754661 was found to increase the risk of Alzheimer's disease in a recent Whole Genome Association Study. We have carried out an independent study of this genetic variant in 2467 individuals from Spain. We found no evidence of association between the MTHFD1L marker and susceptibility to Alzheimer's disease in our sample.
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