Article
A pilot study examining associations between DYRK1A and α-synuclein dementias.
Neuro-degenerative diseases - 1 Jan 2012
Jones Emma L, Aarsland Dag, Londos Elisabet, Ballard Clive
Abstract excerpt
BACKGROUND: DYRK1A is a kinase targeting several proteins associated with the pathology of dementias, including α-synuclein and amyloid precursor protein. It is not clear if DYRK1A genetics are associated with neurodegenerative conditions. OBJECTIVE: To determine if DYRK1A also has a genetic association with α-synuclein dementias such as dementia with Lewy bodies and Parkinson's disease dementia. METHODS: DNA...
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