Article
The relationship between single nucleotide polymorphisms of the NTRK2 gene and sporadic Alzheimer's disease in the Chinese Han population.
Neuroscience letters - 29 Aug 2013
Zeng Fan, Zou Hai-Qiang, Zhou Hua-Dong, Li Jing, Wang Lin, Cao Hong-Yuan, Yi Xu, Wang Xin, Liang Chun-Rong, Wang Ye-Ran, Zhang An-Qiang, Tan Xiao-Ling, Peng Kai-Run, Zhang Li-Li, Gao Chang-Yue, Xu Zhi-Qiang, Wen Ai-Qing, Lian Yan, Zhou Xin-Fu, Wang Yan-Jiang
Abstract excerpt
Alzheimer's disease (AD) is characterized by the degeneration of basal forebrain cholinergic neurons, whose survival and function are affected by neurotrophins and their receptors. The impaired signaling pathway of brain-derived neurotrophic factor/tropomyosin-related kinase B (BDNF/TrkB) is considered to play an important role in AD pathogenesis. To explore the association of polymorphisms within the NTRK2 gene...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
