Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tau-tubulin kinase-1 gene variants are associated with Alzheimer's disease in Han Chinese.

Neuroscience letters - 10 Mar 2011

Yu Nan-Nan, Yu Jin-Tai, Xiao Jian-Ting, Zhang Hao-Wen, Lu Rui-Chun, Jiang Hong, Xing Zhen-Hua, Tan Lan

Abstract excerpt

Tau-tubuline kinase 1 (TTBK1) is a recently discovered brain-specific protein kinase involved in tau phosphorylation at AD-related sites. A recent large study has identified significant association of two single nucleotide polymorphisms (SNPs) (rs2651206 and rs7764257) in the TTBK1 gene with late-onset Alzheimer's disease (LOAD) in Spanish. Here, we performed a case-control study to clarify whether the risk for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged, 80 and over

Share to Alzheimer Disease

Share to Asian People

Share to Brain Chemistry

Share to Case-Control Studies

Share to Polymorphism, Genetic

Share to Protein Serine-Threonine Kinases

Source

Identifiers

PMID: 21219968
DOI: 10.1016/j.neulet.2011.01.011

Genes

TTBK1
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tau-tubulin kinase-1 gene variants are associated with Alzheimer's disease in Han Chinese.PMID 21219968Read ↗

Genetic variations in tau-tubulin kinase-1 are linked to Alzheimer's disease in a Spanish case-control cohort.Semantic proximity Read ↗

Common variant in PTK2B is associated with late-onset Alzheimer's disease: A replication study and meta-analyses.Semantic proximity Read ↗

Association analysis of GSK3B and MAPT polymorphisms with Alzheimer's disease in Han Chinese.Semantic proximity Read ↗

Association between polymorphisms in transforming growth factor-β1 and sporadic Alzheimer's disease in a Chinese population.Semantic proximity Read ↗

Association of Parkinson's Disease GWAS-Linked Loci with Alzheimer's Disease in Han Chinese.Semantic proximity Read ↗

Association of MAPT haplotypes with Alzheimer’s disease risk and MAPT brain gene expression levelsSemantic proximity Read ↗

Association and heterogeneity at the GAPDH locus in Alzheimer's disease.Semantic proximity Read ↗

Genetic variation in the tau kinases pathway may modify the risk and age at onset of Alzheimer's disease.Semantic proximity Read ↗

Lymphocyte-specific protein tyrosine kinase is a novel risk gene for Alzheimer disease.Semantic proximity Read ↗

LMTK2 and CRB1 are two novel risk genes for Alzheimer's disease in Han ChineseSemantic proximity Read ↗

Common and rare TBK1 variants in early-onset Alzheimer disease in a European cohort.Semantic proximity Read ↗

Association of TOMM40 polymorphisms with late-onset Alzheimer's disease in a Northern Han Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.