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Article

No association of CDK5 genetic variants with Alzheimer's disease risk.

BMC medical genetics - 17 Jul 2009

Vázquez-Higuera José Luis, Mateo Ignacio, Sánchez-Juan Pascual, Rodríguez-Rodríguez Eloy, Infante Jon, Berciano José, Combarros Onofre

Abstract excerpt

BACKGROUND: As cyclin-dependent kinase 5 (CDK5) has been implicated in the abnormal hyperphosphorylation of tau in Alzheimer's disease (AD) brain, and the development of neurofibrillary tangles, we examined the contribution of this gene to the susceptibility for AD. METHODS: We examined genetic variations of CDK5 by genotyping haplotype tagging SNPs (htSNPs) (rs9278, rs2069459, rs891507, rs2069454, rs1549759 and...

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Source

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Identifiers

PMID: 19615060
DOI: 10.1186/1471-2350-10-68
PMCID: PMC2716333

Genes

CDK5
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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