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Article

TLR-related pathway analysis: novel gene-gene interactions in the development of asthma and atopy.

Allergy - 1 Feb 2010

Reijmerink N E, Bottema R W B, Kerkhof M, Gerritsen J, Stelma F F, Thijs C, van Schayck C P, Smit H A, Brunekreef B, Koppelman G H, Postma D S

Abstract excerpt

BACKGROUND: The toll-like receptor (TLR)-related pathway is important in host defence and may be crucial in the development of asthma and atopy. Numerous studies have shown associations of TLR-related pathway genes with asthma and atopy phenotypes. So far it has not been investigated whether gene-gene interactions in this pathway contribute to atopy and asthma development. METHODS: One hundred and sixty-nine...

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Source

Identifiers

PMID: 19968634
DOI: 10.1111/j.1398-9995.2009.02111.x

Genes

NOD1
TLR4
BPI
IRAK1
NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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