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Article

Toll-like receptors and microbial exposure: gene-gene and gene-environment interaction in the development of atopy.

The European respiratory journal - 1 Oct 2011

Reijmerink N E, Kerkhof M, Bottema R W B, Gerritsen J, Stelma F F, Thijs C, van Schayck C P, Smit H A, Brunekreef B, Postma D S, Koppelman G H

Abstract excerpt

Environmental and genetic factors contribute to atopy development. High microbial exposure may confer a protective effect on atopy. Toll-like receptors (TLRs) bind microbial products and are important in activating the immune system. To assess whether interactions between microbial exposures and genes encoding TLRs (and related genes) result in atopy, genes, environmental factors and gene-environment interactions...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21349911
DOI: 10.1183/09031936.00099210

Genes

LBP
TLR6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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